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Pierre Marquet

Médecin clinicien enseignant titulaire

Pierre.Marquet@neuro.ulaval.ca
Pavillon Ferdinand-Vandry
1050, avenue de la Médecine
Local 4873

Unité de rattachement — Faculté
Médecine

Affiliations
Centre d'optique, photonique et laser
Centre thématique de recherche en neurosciences
Centre de recherche CERVO

Centre d'optique, photonique et lasers
Programme: Regroupements stratégiques NT
Organisme(s) subventionnaire(s): École polytechnique de Montréal, Université du Québec à Trois-Rivières, École de technologie supérieure, Université de Sherbrooke, Université Concordia, Université Laval - Fonds internes, Institut national de recherche scientifique (INRS), Fonds de recherche du Québec - Nature et technologies, Université McGill
Type de financement: Subvention
Établissement tête: Université Laval
Du 1 avril 2024 au 31 mars 2030

Development of a methodology based on digital holographic microscopy to study cell homeostasis by measuring cell volume dynamics and water fluxes
Programme: Subventions à la découverte SD (individuelles et d'équipe)
Organisme(s) subventionnaire(s): Conseil de recherches en sciences naturelles et génie Canada
Type de financement: Subvention
Établissement tête: Université Laval
Du 1 avril 2024 au 31 mars 2029

Repousser les frontières de l'étude de la biologie à l'échelle nanométrique en conditions naturelles
Programme: Fonds d'innovation (FI)
Organisme(s) subventionnaire(s): Fondation Canadienne pour l'innovation (La), CIUSSS-CN CERVO, Ministère de l'Économie et de l'Innovation et de l'énergie, Ministère de la Santé et des Services sociaux
Type de financement: Subvention
Établissement tête: Université Laval
Du 1 juillet 2023 au 31 mars 2025

Unité mixte internationale (UMI) en neuro-développement et psychiatrie de l’enfant
Programme: BDR - Contributions
Organisme(s) subventionnaire(s): Université Laval - Fonds internes
Type de financement: Subvention
Établissement tête: Université Laval
Du 17 mai 2023 au 31 mars 2030

Développement d'un imageur pour diagnostiquer les troubles de l'humeur aux points de services
Programme: Sentinelle Nord - Fonds de maturation
Organisme(s) subventionnaire(s): Secrétariat des programmes interorganismes à l’intention des établissements
Type de financement: Subvention
Établissement tête: Université Laval
Du 1 mai 2023 au 30 avril 2025

Repetitive transcranial magnetic stimulation to prevent mental health disorders
Programme: Nouvelles frontières en recherche
Organisme(s) subventionnaire(s): Secrétariat des programmes interorganismes à l’intention des établissements
Type de financement: Subvention
Établissement tête: Université Laval
Du 1 mars 2022 au 28 février 2025

Télé-NEUROS (Nouvel Environnement Universitaire de Recherche Orchestrée en Santé mentale et cognitive: une télé initiative)
Organisme(s) subventionnaire(s): CIUSSS-CN CERVO, CIUSSS-CN Centre interdisciplinaire de recherche en réadaptation et intégration sociale (CIRRIS), Université Laval - Fonds internes
Type de financement: Subvention
Établissement tête: Université Laval
Du 20 octobre 2020 au 31 mars 2026

Financements des 2 dernières années

Unveiling comprehensive cellular biophysical properties using quantitative phase digital holographic microscopy
Programme: Subventions à la découverte SD (individuelles et d'équipe)
Organisme(s) subventionnaire(s): Secrétariat Inter-Conseils (Canada) (CRSH, CRSNG, IRSC), Conseil de recherches en sciences naturelles et génie Canada
Type de financement: Subvention
Établissement tête: Université Laval
Du 1 avril 2018 au 31 mars 2024

Smart, adaptative, and autonomous sensing
Programme: Programme de formation orientée vers la nouveauté, la collaboration et l'expérience en recherche (FONCER)
Organisme(s) subventionnaire(s): Université Laval - Fonds internes, Sentinelle Nord, Conseil de recherches en sciences naturelles et génie Canada, Secrétariat Inter-Conseils (Canada) (CRSH, CRSNG, IRSC)
Type de financement: Subvention
Établissement tête: Université Laval
Du 1 avril 2017 au 31 mars 2024

Centre d'optique photonique et laser (COPL)
Programme: Regroupements stratégiques NT
Organisme(s) subventionnaire(s): Université de Sherbrooke, École polytechnique de Montréal, Université McGill, Université Concordia, Fonds de recherche du Québec - Nature et technologies, École de technologie supérieure, Université Laval - Fonds internes
Type de financement: Subvention
Établissement tête: Université Laval
Du 1 avril 2017 au 31 mars 2024

Support de Sentinelle Nord à l'Unité mixte internationale en psychiatrie et neurodéveloppement
Programme: Fonds d'excellence en recherche Apogée Canada
Organisme(s) subventionnaire(s): Secrétariat des programmes interorganismes à l’intention des établissements
Type de financement: Subvention
Établissement tête: Université Laval
Du 1 septembre 2015 au 31 mars 2023

Chaire d'excellence en recherche du Canada en neurophotonique
Programme: Programme de chaires d'excellence en recherche du Canada
Organisme(s) subventionnaire(s): Instituts de recherche en santé du Canada, Université Laval - Fonds internes
Type de financement: Subvention
Établissement tête: Université Laval
Du 1 janvier 2015 au 31 décembre 2023

  • Jean-Honoré Julio Henri Laurent, Doctorat en biophotonique
  • Gabrielle Jess, Maîtrise en physique - avec mémoire
  • Corentin Emilien Soubeiran, Doctorat en biophotonique
  • Paul Amaury Parant, Doctorat en physique
  • Céline Larivière-Loiselle, Doctorat en physique
  • Johan Chaniot, Stage postdoctoral en neurobiologie
  • Jodie Llinares, Stage postdoctoral en médecine
  • Mohamed Haouat, Stage postdoctoral en médecine
  • Sara Mattar, Doctorat en neurobiologie
  • Alana Arrouet, Doctorat en neurosciences
  • Niraj Patel, Doctorat en neurobiologie
  • Encadrements terminés dans les 5 dernières années

  • Louis Philippe De Tillieux, Doctorat en physique
  • Philippe Bilodeau, Maîtrise en physique - avec mémoire
  • Antoine Grégoire, Maîtrise en physique - avec mémoire
  • Christophe Perron, Maîtrise en biophotonique - avec mémoire
  • Paul Amaury Parant, Maîtrise en physique - avec mémoire
  • Louis-Philippe Guinard, Maîtrise en biophotonique - avec mémoire
  • Vahid Khojasteh Lazarjan, Doctorat en génie électrique
  • Emile Rioux-Pellerin, Maîtrise en biophotonique - avec mémoire
  • Bertrand De Dorlodot, Maîtrise en biophotonique - avec mémoire
  • Céline Larivière-Loiselle, Maîtrise en physique - avec mémoire
  • Andréanne Deschênes, Maîtrise en biophotonique - avec mémoire
  • Pauline Lavergne, Maîtrise en neurosciences - avec mémoire
  • Publications des 5 dernières années

    Activities of clinical pharmacologists across Europe: A survey by the European association of clinical pharmacology and therapeutics European Journal of Clinical Pharmacology, 2024/06. Pierre Marquet, Emilie Jouanjus, Joaquin Sáez-Peñataro, Aranzazu Sancho-Lopez. DOI 10.1007/s00228-024-03657-x

    Bridging the Worlds of Pharmacometrics and Machine Learning Clinical Pharmacokinetics, 2023/11. Kamilė Stankevičiūtė, Jean-Baptiste Woillard, Richard W. Peck, Pierre Marquet, Mihaela van der Schaar. DOI 10.1007/s40262-023-01310-x

    Active or passive maternal smoking increases the risk of low birth weight or preterm delivery: Benefits of cessation and tobacco control policies Tobacco Induced Diseases, 2023/05/29. Michel-Henri Delcroix, Conchita Delcroix-Gomez, Pierre Marquet, Tristan Gauthier, Daniel Thomas, Yves Aubard. DOI 10.18332/tid/156854

    New perspectives for the therapeutic drug monitoring of tacrolimus: Quantification in volumetric DBS based on an automated extraction and LC-MS/MS analysis. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2023/04. Rosé G, Tafzi N, El Balkhi S, Rerolle JP, Debette-Gratien M, Marquet P, Saint-Marcoux F, Monchaud C. DOI 10.1016/j.jchromb.2023.123721

    Modulation of Monocyte Response by MicroRNA-15b/106a/374a During Antibody-mediated Rejection in Kidney Transplantation. Transplantation, 2023/04. Tinel C, Lamarthée B, Gazut S, Van Loon E, Von Tokarski F, Benon A, Sauvaget V, Garcia-Paredes V, Ménager M, Morin L, Aouni L, Cagnard N, Rabant M, Anglicheau D. DOI 10.1097/tp.0000000000004393

    Does the Tacrolimus Trough Level Adequately Predict Drug Exposure in Patients Requiring a High Tacrolimus Dose? Transplantation direct, 2023/03. Haverals L, Roosens L, Wouters K, Marquet P, Monchaud C, Massart A, Abramowicz D, Hellemans R. DOI 10.1097/txd.0000000000001439

    A Hybrid Algorithm Combining Population Pharmacokinetic and Machine Learning for Isavuconazole Exposure Prediction. Pharmaceutical research, 2023/03. Destere A, Marquet P, Labriffe M, Drici MD, Woillard JB. DOI 10.1007/s11095-023-03507-y

    [History of pharmacology-toxicology in Limoges]. Therapie, 2023/02. Marquet P, Laroche ML, Merle L, Lachâtre G, au nom de la pharmacologie-toxicologie Limousine. DOI 10.1016/j.therap.2023.02.003

    Ultrafast Measurement of Metformin in the Clinical Setting Using Probe Electrospray Ionization Mass Spectrometry. Journal of analytical toxicology, 2023/02. Griffeuille P, El Balkhi S, Bodeau S, Lamoureux F, Marquet P, Dulaurent S, Saint-Marcoux F. DOI 10.1093/jat/bkac034

    Substrate binding and lipid-mediated allostery in the human organic anion transporter 1 at the atomic-scale. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023/02. Janaszkiewicz A, Tóth Á, Faucher Q, Arnion H, Védrenne N, Barin-Le Guellec C, Marquet P, Di Meo F. DOI 10.1016/j.biopha.2023.114342

    Mycophenolate Mofetil Dose Adjustment in Pediatric Kidney Transplant Recipients. Therapeutic drug monitoring, 2023/02. Labriffe M, Micallef L, Woillard JB, Monchaud C, Saint-Marcoux F, Debord J, Marquet P. DOI 10.1097/ftd.0000000000001087

    Longitudinal Exposure to Tacrolimus and New-Onset Diabetes Mellitus in Renal Transplant Patients. Therapeutic drug monitoring, 2023/02. Destere A, Premaud A, Monchaud C, Marquet P, Woillard JB. DOI 10.1097/ftd.0000000000001035

    Application of machine learning to predict tacrolimus exposure in liver and kidney transplant patients given the MeltDose formulation. European journal of clinical pharmacology, 2022/12. Ponthier L, Marquet P, Moes DJAR, Rostaing L, van Hoek B, Monchaud C, Labriffe M, Woillard JB. DOI 10.1007/s00228-022-03445-5

    Can the Area Under the Curve/Trough Level Ratio Be Used to Optimize Tacrolimus Individual Dose Adjustment? Transplantation, 2022/11. Woillard JB, Monchaud C, Saint-Marcoux F, Labriffe M, Marquet P. DOI 10.1097/tp.0000000000004405

    Fetal growth restriction, low birth weight, and preterm birth: Effects of active or passive smoking evaluated by maternal expired CO at delivery, impacts of cessation at different trimesters Tobacco Induced Diseases, 2022/08/26. Conchita Delcroix-Gomez, Michel-Henri Delcroix, Amal Jamee, Tristan Gauthier, Pierre Marquet, Yves Aubard. DOI 10.18332/tid/152111

    Uterine Factor Infertility, a Systematic Review. Journal of clinical medicine, 2022/08. Sallée C, Margueritte F, Marquet P, Piver P, Aubard Y, Lavoué V, Dion L, Gauthier T. DOI 10.3390/jcm11164907

    Pharmacokinetics, Pharmacodynamics, and Therapeutic Drug Monitoring of Valganciclovir and Ganciclovir in Transplantation Clinical Pharmacology & Therapeutics, 2022/08. Bénédicte Franck, Julie Autmizguine, Pierre Marquet, Philippe Ovetchkine, Jean‐Baptiste Woillard. DOI 10.1002/cpt.2431

    Optimization of Vancomycin Initial Dose in Term and Preterm Neonates by Machine Learning. Pharmaceutical research, 2022/08. Ponthier L, Ensuque P, Destere A, Marquet P, Labriffe M, Jacqz-Aigrain E, Woillard JB. DOI 10.1007/s11095-022-03351-6

    Machine learning algorithms to estimate everolimus exposure trained on simulated and patient pharmacokinetic profiles CPT: Pharmacometrics & Systems Pharmacology, 2022/08. Marc Labriffe, Jean‐Baptiste Woillard, Jean Debord, Pierre Marquet. DOI 10.1002/psp4.12810

    Substrate binding and lipid-mediated allostery in the human organic anion transporter 1 at the atomic-scale 2022/07/15. Angelika Janaszkiewicz, Ágota Tóth, Quentin Faucher, Hélène Arnion, Nicolas Védrenne, Chantal Barin-Le Guellec, Pierre Marquet, Florent Di Meo. DOI 10.1101/2022.07.14.500056

    Transcriptional and spatial profiling of the kidney allograft unravels a central role for FcyRIII+ innate immune cells in rejection 2022/07. Lamarthée B, Callemeyn J, Herck YV, Antoranz A, Anglicheau D, Becker JU, Debyser T, Smet FD, Vusser KD, Eloudzeri M, Franken A, Gwinner W, Koshy P, Naesens M. DOI 10.1101/2022.07.07.22276374

    Is Intestinal Dysbiosis-Associated With Immunosuppressive Therapy a Key Factor in the Pathophysiology of Post-Transplant Diabetes Mellitus? Frontiers in endocrinology, 2022/07. Faucher Q, Jardou M, Brossier C, Picard N, Marquet P, Lawson R. DOI 10.3389/fendo.2022.898878

    Population pharmacokinetics and Bayesian estimation of mycophenolate mofetil in patients with autoimmune hepatitis. British journal of clinical pharmacology, 2022/05. Nanga TM, Woillard JB, Rousseau A, Marquet P, Prémaud A. DOI 10.1111/bcp.15389

    Biological pathways and comparison with biopsy signals and cellular origin of peripheral blood transcriptomic profiles during kidney allograft pathology. Kidney international, 2022/05. Van Loon E, Lamarthée B, de Loor H, Van Craenenbroeck AH, Brouard S, Danger R, Giral M, Callemeyn J, Tinel C, Cortés Calabuig Á, Koshy P, Naesens M. DOI 10.1016/j.kint.2022.03.026

    A Hybrid Model Associating Population Pharmacokinetics with Machine Learning: A Case Study with Iohexol Clearance Estimation. Clinical pharmacokinetics, 2022/05. Destere A, Marquet P, Gandonnière CS, Åsberg A, Loustaud-Ratti V, Carrier P, Ehrmann S, Guellec CB, Premaud A, Woillard JB. DOI 10.1007/s40262-022-01138-x

    Perfusate Metabolomics Content and Expression of Tubular Transporters During Human Kidney Graft Preservation by Hypothermic Machine Perfusion. Transplantation, 2022/04. Faucher Q, Alarcan H, Sauvage FL, Forestier L, Miquelestorena-Standley E, Nadal-Desbarats L, Arnion H, Venhard JC, Brichart N, Bruyère F, Marquet P, Barin-Le Guellec C. DOI 10.1097/tp.0000000000004129

    Noninvasive Diagnosis of Acute Rejection in Renal Transplant Patients Using Mass Spectrometric Analysis of Urine Samples: A Multicenter Diagnostic Phase III Trial. Transplantation direct, 2022/04. Gwinner W, Karch A, Braesen JH, Khalifa AA, Metzger J, Naesens M, Van Loon E, Anglicheau D, Marquet P, Budde K, Matz M, Arns W, Fischereder M, Koch A. DOI 10.1097/txd.0000000000001316

    Insights into the structure and function of the human organic anion transporter 1 in lipid bilayer membranes. Scientific reports, 2022/04. Janaszkiewicz A, Tóth Á, Faucher Q, Martin M, Chantemargue B, Barin-Le Guellec C, Marquet P, Di Meo F. DOI 10.1038/s41598-022-10755-2

    A Machine Learning Approach to Predict Interdose Vancomycin Exposure. Pharmaceutical research, 2022/04. Bououda M, Uster DW, Sidorov E, Labriffe M, Marquet P, Wicha SG, Woillard JB. DOI 10.1007/s11095-022-03252-8

    Urinary collagen-derived peptides as sensitive markers for bone resorption and bisphosphonate treatment in kidney transplant patients 2022/02. Marx D, Anglicheau D, Caillard S, Moulin B, Kochman A, Mischak H, Pejchinowski M, Latosinska A, Bienaimé F, Prié D, Marquet P, Perrin P, Gwinner W, Metzger J. DOI 10.1101/2022.02.15.22270979

    Insights into the structure and function of the human organic anion transporter 1 in lipid bilayer membranes 2022/01/12. Angelika Janaszkiewicz, Ágota Tóth, Quentin Faucher, Marving Martin, Benjamin Chantemargue, Chantal Barin-Le Guellec, Pierre Marquet, Florent Di Meo. DOI 10.1101/2022.01.10.475390

    Metabolic interactions of benzodiazepines with oxycodone ex vivo and toxicity depending on usage patterns in an animal model. British journal of pharmacology, 2022/01. Lawson R, Čechová P, Zarrouk E, Javellaud J, Bazgier V, Otyepka M, Trouillas P, Picard N, Marquet P, Saint-Marcoux F, El Balkhi S. DOI 10.1111/bph.15765

    How has the future investment program stimulated research and innovation in health? Therapie, 2022/01. Bordet R, Dantonel JC, Vacaresse E, Le Jeunne C, Benhabiles N, Beretz A, Boitard C, Debette S, Duluc G, Froguel P, Garbil B, Lyonnet S, Mahfoudi A, Zins M. DOI 10.1016/j.therap.2022.01.009

    Comment le programme d’investissements d’avenir a-t-il stimulé la recherche et l’innovation en santé ? Therapie, 2022/01. Bordet R, Dantonel JC, Vacaresse E, Le Jeunne C, Benhabiles N, Beretz A, Boitard C, Debette S, Duluc G, Froguel P, Garbil B, Lyonnet S, Mahfoudi A, Zins M. DOI 10.1016/j.therap.2022.01.005

    A single Bayesian estimator for iohexol clearance estimation in ICU, liver failure and renal transplant patients. British journal of clinical pharmacology, 2022/01. Destere A, Salmon Gandonnière C, Åsberg A, Loustaud-Ratti V, Carrier P, Ehrmann S, Barin-Le Guellec C, Marquet P, Woillard JB. DOI 10.1111/bcp.15197

    Therapeutic Drug Monitoring in the Era of Precision Medicine: Achievements, Gaps, and Perspectives-An Interview in Honor of Professor Charles Pippenger. Therapeutic drug monitoring, 2021/12. Wong SH, Marquet P, Cattaneo D, Svinarov D, Bergan S, Walson P, Vinks AA, Shipkova M. DOI 10.1097/ftd.0000000000000932

    Population Pharmacokinetics And Bayesian Estimation of Mycophenolate Mofetil In Patients With Autoimmune Hepatitis 2021/11. Nanga T, Woillard J, Rousseau A, Marquet P, Prémaud A. DOI 10.22541/au.163577198.80163436/v1

    Integrative Omics Analysis Unravels Microvascular Inflammation-Related Pathways in Kidney Allograft Biopsies. Frontiers in immunology, 2021/11. Tinel C, Lamarthée B, Callemeyn J, Van Loon E, Sauvaget V, Morin L, Aouni L, Rabant M, Gwinner W, Marquet P, Naesens M, Anglicheau D. DOI 10.3389/fimmu.2021.738795

    Therapeutic education as a tool to improve patient-reported and clinical outcomes after renal transplantation: results of the EPHEGREN multicenter retrospective cohort study. Transplant international : official journal of the European Society for Organ Transplantation, 2021/10. Villeneuve C, Rerolle JP, Couzi L, Westeel PF, Etienne I, Esposito L, Kamar N, Büchler M, Thierry A, Marquet P, Monchaud C. DOI 10.1111/tri.14127

    Machine learning-supported interpretation of kidney graft elementary lesions in combination with clinical data 2021/09/22. Marc Labriffe, Jean-Baptiste Woillard, Wilfried Gwinner, Jan-Hinrich Braesen, Dany Anglicheau, Marion Rabant, Priyanka Koshy, Maarten Naesens, Pierre Marquet. DOI 10.1101/2021.09.17.21263552

    Perfusate metabolomics content and tubular transporters expression during kidney graft preservation by hypothermic machine perfusion 2021/09. Faucher Q, Alarcan H, Sauvage F, Forestier L, Miquelestorena-Standley E, Nadal-Desbarats L, Arnion H, Venhard J, Brichart N, Bruyère F, Marquet P, Guellec CB. DOI 10.1101/2021.09.27.21264167

    Multi-omics investigation of tacrolimus nephrotoxicity 2021/07. Aouad H, Faucher Q, Sauvage F, Pinault E, Barrot C, Arnion H, Marquet P, Essig M. DOI 10.1101/2021.07.29.454229

    Thoroughly Validated Bayesian Estimator and Limited Sampling Strategy for Dose Individualization of Ganciclovir and Valganciclovir in Pediatric Transplant Recipients. Clinical pharmacokinetics, 2021/05/29. DOI 10.1007/s40262-021-01034-w

    Clinical Pharmacokinetics and Bayesian Estimators for the Individual Dose Adjustment of a Generic Formulation of Tacrolimus in Adult Kidney Transplant Recipients Clinical Pharmacokinetics, 2021/05/24. Pierre Marquet, Alexandre Destère, Caroline Monchaud, Jean-Philippe Rérolle, Matthias Buchler, Hakim Mazouz, Isabelle Etienne, Antoine Thierry, Nicolas Picard, Jean-Baptiste Woillard, Jean Debord. DOI 10.1007/s40262-020-00959-y

    High-throughput sequencing defines donor and recipient HLA B-cell epitope frequencies for prospective matching in transplantation. Communications biology, 2021/05/14. DOI 10.1038/s42003-021-01989-3

    Towards therapeutic drug monitoring of mycophenolic acid in mucous membrane pemphigoid: A retrospective single-centre study. Fundamental & clinical pharmacology, 2021/04/29. DOI 10.1111/fcp.12688

    Personalized Therapy for Mycophenolate: Consensus Report by the International Association of Therapeutic Drug Monitoring and Clinical Toxicology. Therapeutic drug monitoring, 2021/04/01. DOI 10.1097/ftd.0000000000000871

    Estimation of drug exposure by machine learning based on simulations from published pharmacokinetic models: The example of tacrolimus. Pharmacological research, 2021/03/26. DOI 10.1016/j.phrs.2021.105578

    First-Line Toxicological Screening with Fully Automated Extraction. Journal of analytical toxicology, 2021/03/01. DOI 10.1093/jat/bkaa075

    Mycophenolic acid exposure prediction using machine learning. Clinical pharmacology and therapeutics, 2021/02/24. DOI 10.1002/cpt.2216

    A Machine Learning Approach to Estimate the Glomerular Filtration Rate in Intensive Care Unit Patients Based on Plasma Iohexol Concentrations and Covariates. Clinical pharmacokinetics, 2021/02/01. DOI 10.1007/s40262-020-00927-6

    Population pharmacokinetics of ganciclovir and valganciclovir in paediatric solid organ and stem cell transplant recipients. British journal of clinical pharmacology, 2020/12/29. DOI 10.1111/bcp.14719

    A Population Pharmacokinetic Modeling Approach to Determine the Efficacy of Intravenous Amikacin in Children with Cystic Fibrosis. Therapeutic drug monitoring, 2020/12/17. DOI 10.1097/ftd.0000000000000855

    Immunosuppressant quantification in intravenous microdialysate - towards novel quasi-continuous therapeutic drug monitoring in transplanted patients. Clinical chemistry and laboratory medicine, 2020/12/15. DOI 10.1515/cclm-2020-1542

    Analyses of AUC(0-12) and C0 Compliances within Therapeutic Ranges in Kidney Recipients Receiving Cyclosporine or Tacrolimus. Journal of clinical medicine, 2020/12/01. DOI 10.3390/jcm9123903

    Tacrolimus Exposure Prediction Using Machine Learning. Clinical pharmacology and therapeutics, 2020/11/30. DOI 10.1002/cpt.2123

    The scientific basis of rational prescribing. A guide to precision clinical pharmacology based on the WHO 6-step method. European journal of clinical pharmacology, 2020/11/18. DOI 10.1007/s00228-020-03044-2

    Tacrolimus Bayesian dose adjustment in pediatric renal transplant recipients. Therapeutic drug monitoring, 2020/10/30. DOI 10.1097/ftd.0000000000000828

    MRP4 is responsible for the efflux transport of mycophenolic acid β-d glucuronide (MPAG) from hepatocytes to blood. Xenobiotica; the fate of foreign compounds in biological systems, 2020/09/06. DOI 10.1080/00498254.2020.1813352

    Effects of Ischemia-Reperfusion on Tubular Cell Membrane Transporters and Consequences in Kidney Transplantation. Journal of clinical medicine, 2020/08/12. DOI 10.3390/jcm9082610

    Phenotyping of Uracil and 5-Fluorouracil Metabolism Using LC-MS/MS for Prevention of Toxicity and Dose Adjustment of Fluoropyrimidines. Therapeutic drug monitoring, 2020/08/01. DOI 10.1097/ftd.0000000000000768

    Antibody-mediated rejection with and without donor-specific anti-human leucocyte antigen antibodies: performance of the peripheral blood 8-gene expression assay. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2020/08/01. DOI 10.1093/ndt/gfaa096

    Transcriptional Changes in Kidney Allografts with Histology of Antibody-Mediated Rejection without Anti-HLA Donor-Specific Antibodies. Journal of the American Society of Nephrology : JASN, 2020/07/08. DOI 10.1681/asn.2020030306

    Urinary Protein Biomarker Panel for the Diagnosis of Antibody-Mediated Rejection in Kidney Transplant Recipients. Kidney international reports, 2020/06/29. DOI 10.1016/j.ekir.2020.06.018

    Evaluation of Longitudinal Exposure to Tacrolimus as a Risk Factor of Chronic Kidney Disease Occurrence Within the First Year Post-Liver Transplantation. Transplantation, 2020/06/29. DOI 10.1097/tp.0000000000003384

    Development and validation of an optimized integrative model using urinary chemokines for noninvasive diagnosis of acute allograft rejection. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2020/06/27. DOI 10.1111/ajt.15959

    [Summary of the recommendations of the International Association of Therapeutic Drug Monitoring and Clinical Toxicology (IATDMCT) on the therapeutic drug monitoring of tacrolimus]. Therapie, 2020/06/20. DOI 10.1016/j.therap.2020.06.004

    Real life experience of mycophenolate mofetil monotherapy in liver transplant patients. Clinics and research in hepatology and gastroenterology, 2020/06/11. DOI 10.1016/j.clinre.2020.04.017

    Professor Folke Sjöqvist peacefully passed away on March 30, 2020. European journal of clinical pharmacology, 2020/06/10. DOI 10.1007/s00228-020-02911-2

    The FcγRIIIA-158 VV genotype increased the risk of post-transplant lymphoproliferative disorder in T-cell-depleted kidney transplant recipients - a retrospective study. Transplant international : official journal of the European Society for Organ Transplantation, 2020/05/14. DOI 10.1111/tri.13624

    Population pharmacokinetics of gentamicin in haemodialysis patients: modelling, simulations and recommendations. European journal of clinical pharmacology, 2020/05/01. DOI 10.1007/s00228-020-02867-3

    Pharmacokinetic evaluation of MFF in combinations with tacrolimus and cyclosporine. Findings of C0 and AUC. Medicine, 2020/03/01. DOI 10.1097/md.0000000000019441

    Population pharmacokinetics and Bayesian estimators for intravenous mycophenolate mofetil in haematopoietic stem cell transplant patients. British journal of clinical pharmacology, 2020/02/28. DOI 10.1111/bcp.14261

    Automatic quantification of uracil and dihydrouracil in plasma. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2020/02/21. DOI 10.1016/j.jchromb.2020.122038

    Toward a robust tool for pharmacokinetic-based personalization of treatment with tacrolimus in solid organ transplantation: A model-based meta-analysis approach. British journal of clinical pharmacology, 2019/12/17. DOI 10.1111/bcp.14110

    Health research and innovation: Can we optimize the interface between startups/pharmaceutical companies and academic health care institutions or not? Therapie, 2019/12/14. DOI 10.1016/j.therap.2019.11.010

    Recherche et innovation en santé : comment optimiser l’interface entre les startups/industries et les établissements de santé académiques ou non ? Therapie, 2019/12/13. DOI 10.1016/j.therap.2019.11.006

    Metabolic alterations of uterine grafts after extended cold ischemic storage: experimental study in ewes. Molecular human reproduction, 2019/10/01. DOI 10.1093/molehr/gaz041

    Comparison of Tacrolimus Starting Doses Based on CYP3A5 Phenotype or Genotype in Kidney Transplant Recipients. Progress in transplantation (Aliso Viejo, Calif.), 2019/09/12. DOI 10.1177/1526924819873905

    Cyclosporine A inhibits MRTF-SRF signaling through Na+/K+ ATPase inhibition and actin remodeling. FASEB bioAdvances, 2019/08/24. DOI 10.1096/fba.2019-00027

    Adherence profiles in kidney transplant patients: Causes and consequences. Patient education and counseling, 2019/08/07. DOI 10.1016/j.pec.2019.08.002

    Development and validation of a peripheral blood mRNA assay for the assessment of antibody-mediated kidney allograft rejection: A multicentre, prospective study. EBioMedicine, 2019/08/01. DOI 10.1016/j.ebiom.2019.07.028

    Evaluation of a non-parametric modelling for meropenem in critically ill patients using Monte Carlo simulation. European journal of clinical pharmacology, 2019/07/23. DOI 10.1007/s00228-019-02716-y

    Impairing temozolomide resistance driven by glioma stem-like cells with adjuvant immunotherapy targeting O-acetyl GD2 ganglioside. International journal of cancer, 2019/07/13. DOI 10.1002/ijc.32533

    Towards a Generic Tool for Prediction of Meropenem Systemic and Infection-Site Exposure: A Physiologically Based Pharmacokinetic Model for Adult Patients with Pneumonia Drugs in R&D, 2019/06. DOI 10.1007/s40268-019-0268-x

    Therapeutic Drug Monitoring of Tacrolimus-Personalized Therapy Therapeutic Drug Monitoring, 2019/06. DOI 10.1097/ftd.0000000000000640

    The European Association for Clinical Pharmacology and Therapeutics—25 years’ young and going strong European Journal of Clinical Pharmacology, 2019/06. DOI 10.1007/s00228-019-02690-5

    The Key Role of Warm and Cold Ischemia in Uterus Transplantation: A Review. Journal of clinical medicine, 2019/05/29. DOI 10.3390/jcm8060760

    Sum of peak intensities outperforms peak area integration in iTRAQ protein expression measurement by LC-MS/MS using a TripleTOF 5600+ platform. Bioscience Reports, 2019/05/20. DOI 10.1042/bsr20190904

    Changes in the metabolic composition of storage solution with prolonged cold ischemia of the uterus Journal of Assisted Reproduction and Genetics, 2019/05/12. DOI 10.1007/s10815-019-01477-y

    Population pharmacokinetic model and Bayesian estimator for two tacrolimus formulations in adult liver transplant patients British Journal of Clinical Pharmacology, 2019/04/11. DOI 10.1111/bcp.13960

    A Prognostic Tool for Individualized Prediction of Graft Failure Risk within Ten Years after Kidney Transplantation Journal of Transplantation, 2019/04/08. DOI 10.1155/2019/7245142

    Pharmacodynamic Monitoring of mTOR Inhibitors Therapeutic Drug Monitoring, 2019/04. DOI 10.1097/ftd.0000000000000616

    2019 American Transplant Congress Abstracts. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2019/04/01. DOI 10.1111/ajt.15405


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