Répertoire du corps professoral
Patrice Brassard
Professeur titulaire
(418) 656-2131, poste 405621
Patrice.Brassard@kin.ulaval.ca
Pavillon Éduc. phys. et sports
2300, rue de la Terrasse
Local 0290H
Séquenceur de gaz et moniteur non-invasif de pression artérielle pour la recherche et l'innovation en physiologie vasculaire cérébrale
Programme: Fonds des leaders John-R.-Evans (FLJR)
Organisme(s) subventionnaire(s): Ministère de la Santé et des Services sociaux, Fondation Canadienne pour l'innovation (La), Fondation IUCPQ
Type de financement: Subvention
Établissement tête: Université Laval
Du 1 juillet 2022
au31 décembre 2024
Cerebral blood flow regulation during acute increases in blood pressure: Can cerebral sympathetic nervous activity act as a gatekeeper?
Programme: Subventions à la découverte SD (individuelles et d'équipe)
Organisme(s) subventionnaire(s): Conseil de recherches en sciences naturelles et génie Canada
Type de financement: Subvention
Établissement tête: Université Laval
Du 1 avril 2020
au31 mars 2027
Financements des 2 dernières années
Comparing the effects of cognitive training and physical exercise on cognition, cerebral autoregulation and cerebral vasoreactivity in men and women with heart failure
Programme: Subvention Projet
Organisme(s) subventionnaire(s): Instituts de recherche en santé du Canada
Type de financement: Subvention
Établissement tête: Université Concordia
Du 1 avril 2019
au31 mars 2023
Encadrements terminés dans les 5 dernières années
Publications des 5 dernières années
My sojourn with cerebral sympathetic nervous activity Experimental Physiology, 2024/10. Patrice Brassard. DOI 10.1113/EP092029
Time-domain methods for quantifying dynamic cerebral blood flow autoregulation: Review and recommendations. A white paper from the Cerebrovascular Research Network (CARNet) Journal of Cerebral Blood Flow and Metabolism, 2024. Kostoglou, K., Bello-Robles, F., Brassard, P., Chacon, M., Claassen, J.A.H.R., Czosnyka, M., Elting, J.-W., Hu, K., Labrecque, L., Liu, J., Marmarelis, V.Z., Payne, S.J., Shin, D.C., Simpson, D., Smirl, J., Panerai, R.B., Mitsis, G.D.. DOI 10.1177/0271678X241249276
On the challenge of assessing dynamic cerebral autoregulation Experimental Physiology, 2024. Brassard, P., Roy, M.-A., Labrecque, L., Smirl, J.D.. DOI 10.1113/EP091703
Lower dynamic cerebral autoregulation following acute bout of low-volume high-intensity interval exercise in chronic stroke compared to healthy adults Journal of Applied Physiology, 2024. Whitaker, A.A., Aaron, S.E., Chertoff, M., Brassard, P., Buchanan, J., Nguyen, K., Vidoni, E.D., Waghmare, S., Eickmeyer, S.M., Montgomery, R.N., Billinger, S.A.. DOI 10.1152/japplphysiol.00635.2023
Individual Patient Data Meta-Analysis of Dynamic Cerebral Autoregulation and Functional Outcome after Ischemic Stroke Stroke, 2024. Beishon, L., Vasilopoulos, T., Salinet, A.S.M., Levis, B., Barnes, S., Hills, E., Ramesh, P., Gkargkoula, P., Minhas, J.S., Castro, P., Brassard, P., Goettel, N., Gommer, E.D., Jara, J.L., Liu, J., Mueller, M., Nasr, N., Payne, S., Robertson, A.D., Simpson, D., Robinson, T.G., Panerai, R.B., Nogueira, R.C.. DOI 10.1161/STROKEAHA.123.045700
Exercise-induced potentiation of the acute hypoxic ventilatory response: Neural mechanisms and implications for cerebral blood flow Experimental Physiology, 2024. Oliveira, D.M., Rashid, A., Brassard, P., Silva, B.M.. DOI 10.1113/EP091330
Dynamic cerebral autoregulation quantification with spontaneous arterial blood pressure oscillations: Is transfer function analysis our best option? Experimental Physiology, 2024. Brassard, P., Smirl, J.D.. DOI 10.1113/EP091900
Directional sensitivity of the cerebral pressure-flow relationship during forced oscillations induced by oscillatory lower body negative pressure Journal of Cerebral Blood Flow and Metabolism, 2024. Labrecque, L., Roy, M.-A., Soleimani Dehnavi, S., Taghizadeh, M., Smirl, J.D., Brassard, P.. DOI 10.1177/0271678X241247633
Comparison of the Buffalo Concussion Treadmill Test With a Physiologically Informed Cycle Test: Calgary Concussion Cycle Test Sports Health, 2024. Miutz, L.N., Burma, J.S., Brassard, P., Phillips, A.A., Emery, C.A., Smirl, J.D.. DOI 10.1177/19417381231217744
Acute isometric and dynamic exercise do not alter cerebral sympathetic nerve activity in healthy humans Journal of Cerebral Blood Flow and Metabolism, 2024. Tymko, M.M., Drapeau, A., Vieira-Coelho, M.A., Labrecque, L., Imhoff, S., Coombs, G.B., Langevin, S., Fortin, M., Châteauvert, N., Ainslie, P.N., Brassard, P.. DOI 10.1177/0271678X241248228
A systematic review, meta-analysis and meta-regression amalgamating the driven approaches used to quantify dynamic cerebral autoregulation Journal of Cerebral Blood Flow and Metabolism, 2024. Burma, J.S., Roy, M.-A., Kennedy, C.M., Labrecque, L., Brassard, P., Smirl, J.D.. DOI 10.1177/0271678X241235878
Transfer function analysis of dynamic cerebral autoregulation: A CARNet white paper 2022 update Journal of Cerebral Blood Flow and Metabolism, 2023. Panerai, R.B., Brassard, P., Burma, J.S., Castro, P., Claassen, J.A.H.R., van Lieshout, J.J., Liu, J., Lucas, S.J.E., Minhas, J.S., Mitsis, G.D., Nogueira, R.C., Ogoh, S., Payne, S.J., Rickards, C.A., Robertson, A.D., Rodrigues, G.D., Smirl, J.D., Simpson, D.M.. DOI 10.1177/0271678X221119760
The role of the autonomic nervous system in cerebral blood flow regulation in stroke: A review Autonomic Neuroscience: Basic and Clinical, 2023. Mankoo, A., Roy, S., Davies, A., Panerai, R.B., Robinson, T.G., Brassard, P., Beishon, L.C., Minhas, J.S.. DOI 10.1016/j.autneu.2023.103082
The effect of supine cycling and progressive lower body negative pressure on cerebral blood velocity responses Journal of Applied Physiology, 2023. Miutz, L.N., Burma, J.S., Van Roessel, R.K., Johnson, N.E., Phillips, A.A., Emery, C.A., Brassard, P., Smirl, J.D.. DOI 10.1152/japplphysiol.00758.2022
Quantification of dynamic cerebral autoregulation: welcome to the jungle! Clinical Autonomic Research, 2023. Brassard, P., Roy, M.-A., Burma, J.S., Labrecque, L., Smirl, J.D.. DOI 10.1007/s10286-023-00986-2
Maternal and Fetal Cardiovascular Responses to Acute High-Intensity Interval and Moderate-Intensity Continuous Training Exercise during Pregnancy: A Randomized Crossover Trial Obstetrical and Gynecological Survey, 2023. Wowdzia, J.B., Hazell, T.J., Vanden Berg, E.R., Labrecque, L., Brassard, P., Davenport, M.H.. DOI 10.1097/OGX.0000000000001218
Maternal and Fetal Cardiovascular Responses to Acute High-Intensity Interval and Moderate-Intensity Continuous Training Exercise During Pregnancy: A Randomized Crossover Trial Sports Medicine, 2023. Wowdzia, J.B., Hazell, T.J., Berg, E.R.V., Labrecque, L., Brassard, P., Davenport, M.H.. DOI 10.1007/s40279-023-01858-5
Lower Dynamic Cerebral Autoregulation following Acute Bout of Low-Volume High-Intensity Interval Exercise in Chronic Stroke Compared to Healthy Adults medRxiv, 2023. Whitaker, A.A., Aaron, S.E., Chertoff, M., Brassard, P., Buchanan, J., Nguyen, K., Vidoni, E.D., Waghmare, S., Eickmeyer, S.M., Billinger, S.A.. DOI 10.1101/2023.06.13.23291289
Impact of sex on the cerebrovascular response to incremental aerobic exercise in moderately trained endurance athletes Journal of Applied Physiology, 2023. Chamoun, N., Drapeau, A., Labrecque, L., Imhoff, S., Roy, M.-A., Billaut, F., Rahimaly, K., Brassard, P.. DOI 10.1152/JAPPLPHYSIOL.00749.2022
Habitual exercise in youth: A ʻbrainyʼ idea Experimental Physiology, 2023. Barnes, J.N., Baynard, T., Brassard, P.. DOI 10.1113/EP091534
Cerebral blood flow pulsatility and cerebral artery stiffness acutely decrease during hemodialysis Physiological Reports, 2023. Paré, M., Obeid, H., Labrecque, L., Drapeau, A., Brassard, P., Agharazii, M.. DOI 10.14814/phy2.15595
Trans-cerebral HCO<sub>3</sub><sup>−</sup> and PCO<sub>2</sub> exchange during acute respiratory acidosis and exercise-induced metabolic acidosis in humans Journal of Cerebral Blood Flow and Metabolism, 2022. Caldwell, H.G., Hoiland, R.L., Smith, K.J., Brassard, P., Bain, A.R., Tymko, M.M., Howe, C.A., Carr, J.M.J.R., Stacey, B.S., Bailey, D.M., Drapeau, A., Sekhon, M.S., MacLeod, D.B., Ainslie, P.N.. DOI 10.1177/0271678X211065924
Time-course recovery of cerebral blood velocity metrics post aerobic exercise: a systematic review Journal of Applied Physiology, 2022. Kennedy, C.M., Burma, J.S., Newel, K.T., Brassard, P., Smirl, J.D.. DOI 10.1152/japplphysiol.00630.2021
The role of the autonomic nervous system in cerebral blood flow regulation in dementia: A review Autonomic Neuroscience: Basic and Clinical, 2022. Beishon, L.C., Hosford, P., Gurung, D., Brassard, P., Minhas, J.S., Robinson, T.G., Haunton, V., Panerai, R.B.. DOI 10.1016/j.autneu.2022.102985
Sex-specific effects of cardiorespiratory fitness on age-related differences in cerebral hemodynamics Journal of Applied Physiology, 2022. Zeller, N.P., Miller, K.B., Zea, R.D., Howery, A.J., Labrecque, L., Aaron, S.E., Brassard, P., Billinger, S.A., Barnes, J.N.. DOI 10.1152/japplphysiol.00782.2021
Reproducibility and diurnal variation of the directional sensitivity of the cerebral pressure-flow relationship in men and women Journal of Applied Physiology, 2022. Labrecque, L., Burma, J.S., Roy, M.-A., Smirl, J.D., Brassard, P.. DOI 10.1152/japplphysiol.00653.2021
Prenatal exercise and cardiovascular health (PEACH) study: Impact of acute and chronic exercise on cerebrovascular hemodynamics and dynamic cerebral autoregulation Journal of Applied Physiology, 2022. Skow, R.J., Labrecque, L., Rosenberger, J.A., Brassard, P., Steinback, C.D., Davenport, M.H.. DOI 10.1152/japplphysiol.00446.2021
Point/counterpoint: We should take the direction of blood pressure change into consideration for dynamic cerebral autoregulation quantification Journal of Cerebral Blood Flow and Metabolism, 2022. Labrecque, L., Smirl, J.D., Tzeng, Y.-C., Brassard, P.. DOI 10.1177/0271678X221104868
On the use and misuse of cerebral hemodynamics terminology using transcranial Doppler ultrasound: a call for standardization American Journal of Physiology - Heart and Circulatory Physiology, 2022. Skow, R.J., Brothers, R.M., Claassen, J.A.H.R., Day, T.A., Rickards, C.A., Smirl, J.D., Brassard, P.. DOI 10.1152/ajpheart.00107.2022
Near Infrared Spectroscopy for Poor Grade Aneurysmal Subarachnoid Hemorrhage—A Concise Review Frontiers in Neurology, 2022. Francoeur, C.L., Lauzier, F., Brassard, P., Turgeon, A.F.. DOI 10.3389/fneur.2022.874393
Integrative physiological assessment of cerebral hemodynamics and metabolism in acute ischemic stroke Journal of Cerebral Blood Flow and Metabolism, 2022. Fan, J.-L., Nogueira, R.C., Brassard, P., Rickards, C.A., Page, M., Nasr, N., Tzeng, Y.-C.. DOI 10.1177/0271678X211033732
Integrative cerebral blood flow regulation in ischemic stroke Journal of Cerebral Blood Flow and Metabolism, 2022. Fan, J.-L., Brassard, P., Rickards, C.A., Nogueira, R.C., Nasr, N., McBryde, F.D., Fisher, J.P., Tzeng, Y.-C.. DOI 10.1177/0271678X211032029
Influence of high-intensity interval training to exhaustion on the directional sensitivity of the cerebral pressure-flow relationship in young endurance-trained men Physiological Reports, 2022. Abbariki, F., Roy, M.-A., Labrecque, L., Drapeau, A., Imhoff, S., Smirl, J.D., Brassard, P.. DOI 10.14814/phy2.15384
Early Detection and Correction of Cerebral Desaturation with Noninvasive Oxy-Hemoglobin, Deoxy-Hemoglobin, and Total Hemoglobin in Cardiac Surgery: A Case Series Anesthesia and Analgesia, 2022. Calderone, A., Jarry, S., Couture, E.J., Brassard, P., Beaubien-Souligny, W., Momeni, M., Liszkowski, M., Lamarche, Y., Shaaban-Ali, M., Matta, B., Rochon, A., Lebon, J.-S., Ayoub, C., Martins, M.R., Courbe, A., Deschamps, A., Denault, A.Y.. DOI 10.1213/ANE.0000000000006155
Directional sensitivity of the cerebral pressure–flow relationship in young healthy individuals trained in endurance and resistance exercise Experimental Physiology, 2022. Roy, M.-A., Labrecque, L., Perry, B.G., Korad, S., Smirl, J.D., Brassard, P.. DOI 10.1113/EP090159
What recording duration is required to provide physiologically valid and reliable dynamic cerebral autoregulation transfer functional analysis estimates? Physiological Measurement, 2021. Burma, J.S., Miutz, L.N., Newel, K.T., Labrecque, L., Drapeau, A., Brassard, P., Copeland, P., Macaulay, A., Smirl, J.D.. DOI 10.1088/1361-6579/abf1af
Utilization of the repeated squat-stand model for studying the directional sensitivity of the cerebral pressure-flow relationship Journal of Applied Physiology, 2021. Labrecque, L., Smirl, J.D., Brassard, P.. DOI 10.1152/japplphysiol.00269.2021
Losing the dogmatic view of cerebral autoregulation Physiological Reports, 2021. Brassard, P., Labrecque, L., Smirl, J.D., Tymko, M.M., Caldwell, H.G., Hoiland, R.L., Lucas, S.J.E., Denault, A.Y., Couture, E.J., Ainslie, P.N.. DOI 10.14814/phy2.14982
Influence of an osteopathic manipulative intervention on cerebral blood velocity changes: Do we have the whole story to appropriately interpret the data? Journal of Osteopathic Medicine, 2021. Drapeau, A., Imhoff, S., Brassard, P.. DOI 10.1515/jom-2021-0225
Effects of age and sex on middle cerebral artery blood velocity and flow pulsatility index across the adult lifespan Journal of Applied Physiology, 2021. Alwatban, M.R., Aaron, S.E., Kaufman, C.S., Barnes, J.N., Brassard, P., Ward, J.L., Miller, K.B., Howery, A.J., Labrecque, L., Billinger, S.A.. DOI 10.1152/japplphysiol.00926.2020
Dynamic cerebral autoregulation and cerebrovascular carbon dioxide reactivity in middle and posterior cerebral arteries in young endurance-trained women Journal of Applied Physiology, 2021. Labrecque, L., Drapeau, A., Rahimaly, K., Imhoff, S., Brassard, P.. DOI 10.1152/japplphysiol.00963.2020
Directional sensitivity of the cerebral pressure-flow relationship in middle and posterior cerebral arteries using the repeated squat-stand model: Within-day reproducibility and impact of diurnal variation in young healthy men and women bioRxiv, 2021. Labrecque, L., Burma, J.S., Roy, M.-A., Smirl, J.D., Brassard, P.. DOI 10.1101/2021.07.30.454396
Cerebral vs. Cardiovascular Responses to Exercise in Type 2 Diabetic Patients Frontiers in Physiology, 2021. Kim, Y.-S., van der Ster, B.J.P., Brassard, P., Secher, N.H., van Lieshout, J.J.. DOI 10.3389/fphys.2020.583155
A proposed algorithm for combining transcranial Doppler ultrasound monitoring with cerebral and somatic oximetry: a case report,Proposition d’un algorithme combinant le monitorage échographique par Doppler transcrânien à l’oxymétrie cérébrale et somatique : une présentation de cas Canadian Journal of Anesthesia, 2021. Azzam, M.A., Couture, E.J., Beaubien-Souligny, W., Brassard, P., Gebhard, C.E., Denault, A.Y.. DOI 10.1007/s12630-020-01832-z
Utilization of the repeated squat-stand model for studying the directional behavior of the cerebral pressure-flow relationship bioRxiv, 2020. Labrecque, L., Smirl, J.D., Brassard, P.. DOI 10.1101/2020.12.15.422722
Multi-metrics assessment of dynamic cerebral autoregulation in middle and posterior cerebral arteries in young fit women bioRxiv, 2020. Labrecque, L., Drapeau, A., Rahimaly, K., Imhoff, S., Billaut, F., Brassard, P.. DOI 10.1101/2020.05.25.114447
HIITing the brain with exercise: mechanisms, consequences and practical recommendations Journal of Physiology, 2020. Calverley, T.A., Ogoh, S., Marley, C.J., Steggall, M., Marchi, N., Brassard, P., Lucas, S.J.E., Cotter, J.D., Roig, M., Ainslie, P.N., Wisløff, U., Bailey, D.M.. DOI 10.1113/JP275021
Continuous reduction in cerebral oxygenation during endurance exercise in patients with pulmonary arterial hypertension Physiological Reports, 2020. Malenfant, S., Brassard, P., Paquette, M., Le Blanc, O., Chouinard, A., Bonnet, S., Provencher, S.. DOI 10.14814/phy2.14389
Comparable blood velocity changes in middle and posterior cerebral arteries during and following acute high-intensity exercise in young fit women Physiological Reports, 2020. Labrecque, L., Drapeau, A., Rahimaly, K., Imhoff, S., Billaut, F., Brassard, P.. DOI 10.14814/phy2.14430
Six weeks of high-intensity interval training to exhaustion attenuates dynamic cerebral autoregulation without influencing resting cerebral blood velocity in young fit men Physiological Reports, 2019. Drapeau, A., Labrecque, L., Imhoff, S., Paquette, M., Le Blanc, O., Malenfant, S., Brassard, P.. DOI 10.14814/phy2.14185
Letter to the editor: On the need of considering cardiorespiratory fitness when examining the influence of sex on dynamic cerebral autoregulation American Journal of Physiology - Heart and Circulatory Physiology, 2019. Labrecque, L., Smirl, J.D., Brassard, P.. DOI 10.1152/ajpheart.00152.2019
Implications of habitual endurance and resistance exercise for dynamic cerebral autoregulation Experimental Physiology, 2019. Perry, B.G., Cotter, J.D., Korad, S., Lark, S., Labrecque, L., Brassard, P., Paquette, M., Le Blanc, O., Lucas, S.J.E.. DOI 10.1113/EP087675
Effect of PPARγ agonist on aerobic exercise capacity in relation to body fat distribution in men with type 2 diabetes mellitus and coronary artery disease: A 1-yr randomized study American Journal of Physiology - Endocrinology and Metabolism, 2019. Bastien, M., Poirier, P., Brassard, P., Arsenault, B.J., Bertrand, O.F., Després, J.-P., Costerousse, O., Piché, M.-E.. DOI 10.1152/ajpendo.00505.2018
Dynamic cerebral autoregulation of endurance-trained men following 6 weeks of high-intensity interval training to exhaustion bioRxiv, 2019. Drapeau, A., Labrecque, L., Imhoff, S., Paquette, M., Le Blanc, O., Malenfant, S., Brassard, P.. DOI 10.1101/605667
Dynamic cerebral autoregulation is attenuated in young fit women Physiological Reports, 2019. Labrecque, L., Rahimaly, K., Imhoff, S., Paquette, M., Le Blanc, O., Malenfant, S., Drapeau, A., Smirl, J.D., Bailey, D.M., Brassard, P.. DOI 10.14814/phy2.13984
Cardiac remodeling after six weeks of high-intensity interval training to exhaustion in endurance-trained men American Journal of Physiology - Heart and Circulatory Physiology, 2019. Mahjoub, H., Le Blanc, O.L., Paquette, M., Imhoff, S., Labrecque, L., Drapeau, A., Poirier, P., Bédard, E., Pibarot, P., Brassard, P.. DOI 10.1152/ajpheart.00196.2019
Cardiac remodeling after six weeks of high-intensity interval training to exhaustion in endurance-trained males bioRxiv, 2019. Mahjoub, H., Le Blanc, O., Paquette, M., Imhoff, S., Labrecque, L., Drapeau, A., Poirier, P., Bédard, É., Pibarot, P., Brassard, P.. DOI 10.1101/582924
Blood Pressure Measurement in Severely Obese Patients: Validation of the Forearm Approach in Different Arm Positions American Journal of Hypertension, 2019. Leblanc, M.-E., Auclair, A., Leclerc, J., Bussières, J., Agharazii, M., Hould, F.-S., Marceau, S., Brassard, P., Godbout, C., Grenier, A., Cloutier, L., Poirier, P.. DOI 10.1093/ajh/hpy152
A Practical Approach to Cerebro-Somatic Near-Infrared Spectroscopy and Whole-Body Ultrasound Journal of Cardiothoracic and Vascular Anesthesia, 2019. Denault, A., Shaaban Ali, M., Couture, E.J., Beaubien-Souligny, W., Bouabdallaoui, N., Brassard, P., Mailhot, T., Jacquet-Lagrèze, M., Lamarche, Y., Deschamps, A.. DOI 10.1053/j.jvca.2019.03.039
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