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Andréanne Gagné

Médecin clinicienne enseignante sous octroi adjointe
andreanne.gagne.4@ulaval.ca

Unité de rattachement — Faculté
Médecine

Affiliations
Groupe de recherche en santé respiratoire

Caractérisation des altérations de SMARCA4 et de SMARCA2 dans les adénocarcinomes pulmonaires de stade précoce
Organisme(s) subventionnaire(s): Fondation de l'Université Laval
Type de financement: Subvention
Établissement tête: Université Laval
Du 2 décembre 2024 au 1 décembre 2026

  • Camryn Bass, Maîtrise en médecine moléculaire - avec mémoire
  • Publications des 5 dernières années

    Acquired SMARCA4 alterations: An uncommon contributor to cancer progression in lung adenocarcinomas Lung Cancer, 2025/08. Andréanne Gagné, Joao Victor M. Alessi, Biagio Ricciuti, Giuseppe Lamberti, Mark M. Awad, Lynette M. Sholl. DOI 10.1016/j.lungcan.2025.108644

    Frequency of targetable genetic alterations in resectable lung adenocarcinoma: Results from the LORD project Lung Cancer, 2025/05. Yohan Bossé, Dominique K. Boudreau, Victoria Saavedra Armero, Zhonglin Li, Élody Tremblay, Nathalie Gaudreault, Andréanne Gagné, Patrice Desmeules, Philippe Joubert. DOI 10.1016/j.lungcan.2025.108530

    Whole-slide multiplexed tissue imaging of prostate adenocarcinoma to investigate immune niches in high- versus low-grade tumors. JOURNAL OF CLINICAL ONCOLOGY, 2025. DOI 10.1200/JCO.2025.43.5_SUPPL.224

    Multiomic analysis identifies suppressive myeloid cell populations in human TB granulomas. bioRxiv, 2025. DOI 10.1101/2025.03.10.642376

    Impact of Implementing a Grossing Tumor-margin Distance Threshold for Frozen Section in Oncologic Lung Surgery AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 2025. DOI 10.1097/PAS.0000000000002337

    Computational analysis of whole slide images predicts PD-L1 expression and progression-free survival in immunotherapy-treated non-small cell lung cancer patients JOURNAL OF TRANSLATIONAL MEDICINE, 2025. DOI 10.1186/S12967-025-06487-2

    Clinicopathological Predictors of the Presence of Blood Circulating Tumor DNA in Early-Stage Non-Small Cell Lung Cancers MODERN PATHOLOGY, 2025. DOI 10.1016/J.MODPAT.2025.100744

    Clinicopathologic characteristics, co-mutation landscape, and survival outcomes of KRAS-G12D mutant lung adenocarcinoma in comparison to KRAS-G12C and EGFR-mutated subtypes LUNG CANCER, 2025. DOI 10.1016/J.LUNGCAN.2025.108596

    Cell states and neighborhoods in distinct clinical stages of primary and metastatic esophageal adenocarcinoma CLINICAL CANCER RESEARCH, 2025. DOI 10.1158/1557-3265.AIMACHINE-A046

    Cell states and neighborhoods in distinct clinical stages of primary and metastatic esophageal adenocarcinoma CELL REPORTS MEDICINE, 2025. DOI 10.1016/J.XCRM.2025.102188

    Brief Report: Clinical Characteristics and Outcomes of Patients With Thoracic SMARCA4-Deficient Undifferentiated Tumors JTO CLINICAL AND RESEARCH REPORTS, 2025. DOI 10.1016/J.JTOCRR.2024.100759

    A Comprehensive Evaluation of Clinicopathologic Characteristics, Molecular Features and Prognosis in Lung Adenocarcinoma with an Acinar Component CANCERS, 2025. DOI 10.3390/CANCERS17111825

    Integrating spatial profiles and cancer genomics to identify immune-infiltrated mismatch repair proficient colorectal cancers 2024/09/26. Jeremiah Wala, Ino de Bruijn, Shannon Coy, Andréanne Gagné, Sabrina Chan, Yu-An Chen, John Hoffer, Jeremy Muhlich, Nikolaus Schultz, Sandro Santagata, Peter K Sorger. DOI 10.1101/2024.09.24.614701

    Cell states and neighborhoods in distinct clinical stages of primary and metastatic esophageal adenocarcinoma 2024/08/19. Josephine Yates, Camille Mathey-Andrews, Jihye Park, Amanda Garza, Andréanne Gagné, Samantha Hoffman, Kevin Bi, Breanna Titchen, Connor Hennessey, Joshua Remland, Erin Shannon, Sabrina Camp, Siddhi Balamurali, Shweta Kiran Cavale, Zhixin Li, Akhouri Kishore Raghawan, Agnieszka Kraft, Genevieve Boland, Andrew J. Aguirre, Nilay S. Sethi, Valentina Boeva, Eliezer Van Allen. DOI 10.1101/2024.08.17.608386

    Whole-slide multiplexed tissue imaging of prostate adenocarcinoma reveals distinct immune niches in high- versus low-grade tumors CANCER RESEARCH, 2024. DOI 10.1158/1538-7445.AM2024-5558

    Spatial Profiling of the Tumor Microenvironment of SMARCA4-Mutant NSCLCs Using Whole-Slide Multiplex Fluorescence Imaging JOURNAL OF THORACIC ONCOLOGY, 2024.

    Reporting of Incidental Thrombotic Arteriopathy in Lung Resection Specimens AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 2024. DOI 10.1097/PAS.0000000000002292

    Pulmonary Adenocarcinoma In Situ and Minimally Invasive Adenocarcinomas in European Patients Have Less <i>KRAS</i> and More <i>EGFR</i> Mutations Compared to Advanced Adenocarcinomas INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2024. DOI 10.3390/IJMS25052959

    Implementing a Grossing Tumor Margin Distance Threshold of 2.0 cm for Frozen Section in Oncologic Lung Surgery: A Validation Study LABORATORY INVESTIGATION, 2024.

    Comparative Assessment of Multiple PD-L1 Antibodies on the Same Slide Using Multiplex Tissue-Based Cyclic Immunofluorescence LABORATORY INVESTIGATION, 2024.

    Clinical Outcomes of Resected Pure Ground-Glass, Heterogeneous Ground-Glass, and Part-Solid Pulmonary Nodules AMERICAN JOURNAL OF ROENTGENOLOGY, 2024. DOI 10.2214/AJR.23.30504

    Characteristics and Outcomes of Patients with SMARCA4-Deficient Undifferentiated Thoracic Tumors JOURNAL OF THORACIC ONCOLOGY, 2024.

    CXCL13 Positive Cells Localization Predict Response to Anti-PD-1/PD-L1 in Pulmonary Non-Small Cell Carcinoma CANCERS, 2024. DOI 10.3390/CANCERS16040708

    Association of Clinicopathological and Molecular Features with the Prognosis of KRAS Mutation Subtypes in Lung Adenocarcinoma LABORATORY INVESTIGATION, 2024.

    Tertiary Lymphoid Aggregates as a Predictive Biomarker of Immunotherapy Treatment Response in Patients with NSCLC LABORATORY INVESTIGATION, 2023.

    Single-cell spatial landscapes of the lung tumour immune microenvironment NATURE, 2023. DOI 10.1038/S41586-022-05672-3

    Single-cell spatial landscape of immunotherapy response reveals mechanisms of CXCL13 enhanced antitumor immunity JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2023. DOI 10.1136/JITC-2022-005545

    Generalization optimizing machine learning to improve CT scan radiomics and assess immune checkpoint inhibitors' response in non-small cell lung cancer: a multicenter cohort study FRONTIERS IN ONCOLOGY, 2023. DOI 10.3389/FONC.2023.1196414

    Comparison of Tumor Immune Microenvironment Using Imaging Mass Cytometry in Patients with Synchronous Lung Adenocarcinomas LABORATORY INVESTIGATION, 2023.

    Clinical Impact of Reporting Incidental Thrombotic Arteriopathy in Lung Resection Specimens LABORATORY INVESTIGATION, 2023.

    CXCL13 Positive Cells Predict Response to Anti-PD-1/PD-L1 in Pulmonary Non Small Cell Carcinoma LABORATORY INVESTIGATION, 2023.

    Amplification of wild-type RET and clinical response to selpercatinib for non-small-cell lung cancer (NSCLC) JOURNAL OF CLINICAL ONCOLOGY, 2023.

    Amplification of wild-type <i>RET</i> and clinical response to selpercatinib for non-small-cell lung cancer (NSCLC). JOURNAL OF CLINICAL ONCOLOGY, 2023. DOI 10.1200/JCO.2023.41.16_SUPPL.9123

    Amplification of Wild-Type <i>RET</i> Represents a Novel Molecular Subtype of Several Cancer Types With Clinical Response to Selpercatinib JCO PRECISION ONCOLOGY, 2023. DOI 10.1200/PO.23.00295

    A Simplified Version of the IASLC Grading System for Invasive Pulmonary Adenocarcinomas With Improved Prognosis Discrimination AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 2023. DOI 10.1097/PAS.0000000000002040

    Wait Times and Survival in Lung Cancer Patients across the Province of Quebec, Canada CURRENT ONCOLOGY, 2022. DOI 10.3390/CURRONCOL29050259

    Prognostic value of complex glandular patterns in invasive pulmonary adenocarcinomas HUMAN PATHOLOGY, 2022. DOI 10.1016/J.HUMPATH.2022.07.007

    Gut microbiota and fermentation-derived branched chain hydroxy acids mediate health benefits of yogurt consumption in obese mice NATURE COMMUNICATIONS, 2022. DOI 10.1038/S41467-022-29005-0

    ZNF768 links oncogenic RAS to cellular senescence NATURE COMMUNICATIONS, 2021. DOI 10.1038/S41467-021-24932-W

    ZNF768 Expression Associates with High Proliferative Clinicopathological Features in Lung Adenocarcinoma CANCERS, 2021. DOI 10.3390/CANCERS13164136

    Venous thrombotic events in patients treated with immune checkpoint inhibitors for non-small cell lung cancer: A retrospective multicentric cohort study THROMBOSIS RESEARCH, 2021. DOI 10.1016/J.THROMRES.2021.06.018

    Thrombotic events in patients treated with immune checkpoint inhibitors for non-small cell lung cancer: A retrospective multicentric cohort study. JOURNAL OF CLINICAL ONCOLOGY, 2021. DOI 10.1200/JCO.2021.39.15_SUPPL.E21198

    Heterogeneity of Immune Biomarkers in Patients with Synchronous Lung Adenocarcinomas MODERN PATHOLOGY, 2021.

    Heterogeneity of Immune Biomarkers in Patients with Synchronous Lung Adenocarcinomas LABORATORY INVESTIGATION, 2021.

    Exploring Genomic Heterogeneity of Synchronous Lung Adenocarcinomas by Whole-Exome Sequencing MODERN PATHOLOGY, 2020.

    Exploring Genomic Heterogeneity of Synchronous Lung Adenocarcinomas by Whole-Exome Sequencing LABORATORY INVESTIGATION, 2020.

    Efficacy of immune checkpoint inhibitors in older patients with non-small cell lung cancer: Real-world data from multicentric cohorts in Canada and France JOURNAL OF GERIATRIC ONCOLOGY, 2020. DOI 10.1016/J.JGO.2020.01.002

    Dietary sucrose induces metabolic inflammation and atherosclerotic cardiovascular diseases more than dietary fat in <i>LDLr</i><SUP>-/-</SUP> <i>ApoB</i><SUP>100/100</SUP> mice ATHEROSCLEROSIS, 2020. DOI 10.1016/J.ATHEROSCLEROSIS.2020.05.002

    DLL3 Expression in Small Cell Lung Carcinomas (SCLC) MODERN PATHOLOGY, 2020.

    DLL3 Expression in Small Cell Lung Carcinomas (SCLC) LABORATORY INVESTIGATION, 2020.

    Cross-reactivity between tumor MHC class I-restricted antigens and an enterococcal bacteriophage SCIENCE, 2020. DOI 10.1126/SCIENCE.AAX0701

    Comprehensive assessment of PD-L1 immunohistochemistry on paired tissue and cytology specimens from non-small cell lung cancer LUNG CANCER, 2020. DOI 10.1016/J.LUNGCAN.2020.06.002

    Characterization of Patients with Synchronous Lung Adenocarcinomas in a Caucasian Population According to the IASLC Criteria MODERN PATHOLOGY, 2020.

    Characterization of Patients with Synchronous Lung Adenocarcinomas in a Caucasian Population According to the IASLC Criteria LABORATORY INVESTIGATION, 2020.

    Domaines de recherche

    • Pathologie (sauf la pathologie buccale)
    • Cibles moléculaires du cancer
    • Génétique du cancer
    • Métastases et progression du cancer
    • Diagnostic du cancer
    • Médecine cardiorespiratoire et hématologie, n.c.a.

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